Background and aims: To evaluate the clinical value of tumor growth rate in hepatocellular carcinoma (HCC) patients, we investigated the growth rate of HCC by calculating the tumor volume doubling time (TVDT) and its impact on survival and recurrence. Methods: A retrospective cohort study of 269 HCC patients who underwent two or more pretreatment imaging studies of computed tomography or …
Doubling time of malignant lesions is between 30 and 500 days with a median of 100 days.
series reported by Dr. Chahinian, mean doubling time of epidermoid (95 days) was longer thanthat of adenocarcinoma (61 days), but this could be due to the disparity in the number of patients in each cell type groUp.2 As early as 1956, Collins,3 in describing the use of serial x-ray films in the measurement of doubling time, has pointed out that, Tumor Doubling Time of Primary Lung CancerjUsuda et al. 2241 30L 1.5 2.0 2.5 3.0 LcglOScale (31.6) (1 00) (31 6) (1 000) (days) Log (DT) Figure 2. Distribution after logarithmic conversion of DT. Skewness: 0.7204; kurtosis: -0.0643. as rapidly growing tumors, and those with a DT of more than 113.3 days as slowly growing tumors. The 5-year, Background and Objectives. Melanoma patients have a 20–27% rate of 5?year survival after surgical resection of pulmonary metastases. We evaluated tumor doubling time (TDT) and other prognostic factors in an attempt to identify candidates for pulmonary metastasectomy.
Specific Growth Rate versus Doubling Time for Quantitative …
Doubling time – Wikipedia, Doubling time – calculation of growth rate of a lesion or …
Doubling time – Wikipedia, According to most studies a volume doubling time below 400 days represents a high likelihood of malignancy, whereas a VDT above 500 days is overwhelmingly characteristic of a benign nodule 1,2. With the growing use of software-based volumetry there is recently an increased reliance on VDT as a parameter in CT-based lung cancer screening 3.
The Doubling Time, Doubling Rate & Progression Calculator can be used for the following purposes: Calculation of tumor marker – doubling time and doubling rate. To calculate tumor marker – doubling time and doubling rate with the data of serial measurements of a serum tumor marker. Calculation of tumor volume – doubling time and doubling rate, 4/15/2007 · Tumor growth rate is usually characterized by the tumor volume doubling time (DT). The term DT was introduced 50 years ago and a graphical method was proposed for its estimation ( 13 ). For an exponentially growing tumor, the growth rate is proportional to its volume ( V ): or where SGR and t are the specific growth rate and time, respectively.
The doubling time is time it takes for a population to double in size/value. It is applied to population growth, inflation, resource extraction, consumption of goods, compound interest, the volume of malignant tumours, and many other things that tend to grow over time .When the relative growth rate (not the absolute growth rate) is constant, the quantity undergoes exponential growth and has a …
Doubling Time One cell divides into two, 2 to 4, 4 to 8, 8 to 16 etc. Exponential growth is found in many primary and metastatic malignancies. Use these calculators to determine doubling time . … The natural history of lung cancer : a review based on rates of tumour growth.
